By Isidoro Di Carlo
This booklet bargains an entire assessment on non colorectal non neuroendocrine (NCRNNE) liver metastases and describes intimately the at the moment on hand remedies. every one bankruptcy specializes in the therapy of metastases from a specific fundamental malignancy and in addition presents useful details on prevalence, average background and prognosis. NCRNNE liver metastases are infrequent entities in comparison with colorectal and neuroendocrine metastases, for which the remedies are good codified. whereas extra guides have seemed at the subject in recent times, an in-depth research has to this point been missing. in addition, such a lot released sequence are insufficiently related as they contain sufferers with NCRNNE hepatic metastases from various fundamental malignancies and accordingly disregard variations in tumor habit, frequency of remoted hepatic metastases, reaction to neoadjuvant or adjuvant treatment and period among analysis of the first tumor and the liver metastases. This booklet, with its extra particular procedure, will serve not just as an updated advisor to prognosis and remedy but in addition as a reference on which to base destiny studies.
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Extra resources for Noncolorectal, Nonneuroendocrine Liver Metastases: Diagnosis and Current Therapies
Anyway, in patients needing caval thrombectomy, hypoperfusion is especially dangerous because of an increased risk of thrombosis . In the most series, the most frequent indication to combined renal and hepatic surgery is instead locally advanced renal cell carcinoma. Outcome of combined procedures is reported only in few limited series from literature [26, 27]; therefore, indications, perioperative management, and postoperative outcomes for simultaneous liver and kidney resection remain poorly defined.
Cipriani • L. it © Springer International Publishing Switzerland 2015 I. 1007/978-3-319-09293-5_3 33 34 E. Pinotti et al. About 10 % of liver metastases from kidney cancer are synchronous and 90 % are metachronous. When liver metastases are present in about 25 % of cases are solitary and in 75 % of cases are multiple . The most important risk factors for liver metastases development in patients with kidney cancer are: • Histological subtype: Approximately 85 % of kidney cancers are renal cell carcinoma (RCC), while others are urothelial cancers of the renal pelvis.
A Breast Health Global Initiative 2013 consensus statement. 1 Incidence Kidney cancer is the ninth most frequent cause of malignant tumors in developed countries and accounts for nearly 2 % of all malignancies . The incidence of kidney cancer varies considerably among different populations and regions. Rates are higher in Western and Eastern Europe, North America, and Australia (8–10 cases per 100,000) and lower in Asia, Africa, and the Pacific (1–2 cases per 100,000) . , smoke and obesity) .