Download Concise Guide to Psychopharmacology by Lauren B. Marangell PDF

By Lauren B. Marangell

The definitive pocket reference for handy daily use. This worthy scientific spouse starts off with an outline of the final rules suitable to the secure and potent use of psychotropic drugs. next chapters specialize in the foremost sessions of psychotropic drugs and the issues for which they're prescribed—with the caveat that the nomenclature is a little bit man made simply because, for instance, many antidepressant drugs also are used to regard nervousness issues. Updates for this version in each drug category verify prepared entry to info on new medications and new findings.

  • Antidepressants—Presents clinically appropriate info for selective serotonin reuptake inhibitors, bupropion, venlafaxine, duloxetine, mirtazapine, in addition to tricyclic antidepressants and monoamine oxidase inhibitors, together with information on determining one antidepressant over one other and discontinuing or switching drugs. up-to-date with new details at the attainable threat of elevated suicidality and different capability uncomfortable side effects.
  • Anxiolytics, sedatives, and hypnotics—Discusses using benzodiazepines, zolpidem, and zaleplon, and ramelteon for the therapy of insomnia in addition to diagnosis-specific guidance for using antidepressants within the remedy of tension problems.
  • Antipsychotics—Describes the houses universal to so much antipsychotics, concentrating on odd antipsychotics (clozapine, risperidone, olanzapine, quetiapine, ziprasidone), now used as first-line brokers. New during this variation: the newest findings on security and efficacy, and at the use of antipsychotic brokers in bipolar sickness.
  • Mood stabilizers—-Details using lithium, valproate, carbamazepine, lamotrigine, and different anticonvulsants in stabilizing temper oscillations, and expands at the use of antipsychotics for treating bipolar affliction. With new info at the remedy of mania and combined episodes.
  • Stimulants—Covers the scientific use, contraindications, dangers and uncomfortable side effects, dosing thoughts, and tracking directions for methylphenidate hydrochloride, dextroamphetamine, pemoline, and modafinil, used to regard attention-deficit/hyperactivity sickness in youngsters and young people, narcolepsy, and (potentially) treatment-resistant melancholy and cognitive impairment in adults.
  • Cognitive enhancers—Discusses the scientific use, drug interactions, and uncomfortable side effects of the cholinesterase inhibitors tacrine, donepezil, rivastigmine, and galantamine, which look after functioning and sluggish extra deterioration within the pharmacological administration of cognitive impairment in mild-to-moderate dementia of the Alzheimer's kind. totally up to date to mirror the newest findings at the NMDA receptor antagonist memantine.

jam-packed with sensible info that's effortless to entry through precise tables and charts, this pocket-sized quantity (it actually suits right into a lab coat or jacket pocket) is designed to be instantly necessary for college students, citizens, and clinicians operating in a number of therapy settings, resembling inpatient psychiatry devices, outpatient clinics, consultation-liaison prone, and personal workplaces.

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Extra info for Concise Guide to Psychopharmacology

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Higher doses do not appear to produce significantly greater sedation. Weight Gain The weight gain associated with mirtazapine use may be partially caused by increased appetite. 7 kg over the first 28 weeks of treatment has been reported in several controlled 40 studies (Bremner 1995; Smith et al. 1990). 3 kg after 40 weeks (Thase et al. 2000). Agranulocytosis In preliminary clinical trials, 2 of 2,796 mirtazapine-treated patients developed agranulocytosis, and 1 developed severe neutropenia. All 3 patients recovered after medication discontinuation, and other possible etiologies were present in at least 1 of these individuals.

In a controlled study, Fava and colleagues (2000) found that 27 paroxetine was associated with greater weight gain than were fluoxetine and sertraline. Syndrome of Inappropriate Secretion of Antidiuretic Hormone Case reports have indicated an association between SSRIs and the syndrome of inappropriate secretion of antidiuretic hormone. Symptoms include lethargy, headache, hyponatremia, increased urinary sodium excretion, and hyperosmotic urine. Acute treatment of this syndrome should consist of discontinuation of the drug as well as restriction of fluid intake.

Bupropion’s lack of significant cardiovascular or respiratory toxicity means that it is rarely lethal in overdose. 37 Drug Interactions The combination of bupropion with an MAOI is potentially dangerous, but less so than the combination of serotonergic drugs and MAOIs. Although the practice is not recommended, MAOIs and bupropion have been combined in patients with refractory depression. In vitro data suggest that bupropion is metabolized by CYP 2B6. Bupropion inhibits CYP 2D6. Because of the risk of dosedependent seizures, caution is warranted when bupropion is combined with other medications that might inhibit its metabolism.

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