Download Advances and Technical Standards in Neurosurgery Volume 33 by John D. Pickard, Nejat Akalan, C. Di Rocco, Vinko V. Dolenc, PDF

By John D. Pickard, Nejat Akalan, C. Di Rocco, Vinko V. Dolenc, J. Lobo Antunes, J. J. A. Mooij, J. Schramm, Marc Sindou

This sequence has already develop into a vintage. quite often, one quantity is released in line with 12 months. The advances part provides fields of neurosurgery and comparable parts during which vital contemporary development has been made. The technical criteria part positive factors exact descriptions of ordinary strategies to help younger neurosurgeons of their post-graduate education. The contributions are written via skilled clinicians and are reviewed by means of all individuals of the editorial board.

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Familial chordomas . . . . . . . . . . . . . . . . Telomere maintenance. . . . . . . . . . . . . . . Genome wide studies and genomic integrity . . . . . . . Cell cycle control . . . . . . . . . . . . . . . . . Tumor suppressor genes . . . . . . . . . . . . . . Oncogene activation . . . . . . . . . . . . . . . . Experimental models of chordoma . . . . . . . . . . . Pathology. .

102 LINAC based stereotactic radiotherapies . . . . . . . . . . . . 102 Gamma-Knife radiosurgery . . . . . . . . . . . . . . . . . 103 Brachytherapy. . . . . . . . . . . . . . . . . . . . . . 104 Charged particle radiation therapies. . . . . . . . . . . . . . 104 Predictive factors on outcome after radiation treatment. . . . . . . 105 Complications of radiation therapy . . . . .

Z€ulch [379] in 1956 noted variable clinical behavior among chordomas and differentiated between slowly growing benign chordomas and rapidly growing malignant chordomas. In the same book, Z€ulch also proposed that chordomas arise at anatomical locations where the notochord tissue is not surrounded by cartilage [379]. Heffelfinger, analyzing 155 cases of chordoma and all other cartilaginous tumors treated at Mayo clinic from 1910 to 1973, described a ‘‘chondroid’’ subtype in 1973 [141]. Despite major progress in microneurosurgery in the 1960’s, a hundred years after the first description of chordomas, the treatment was still very disappointing.

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